I'm David, a mad android fan (though of course that went without saying). My most memorable drive was on a visit to the states last November. Having started in Vegas (and no, I wont tell as what happens in Vegas, stays in Vegas) I drove across the Hoover dam and in to Arizona. A nights stop at the Grand Canyon was unbelievable and one of the best drives I had ever been on, that is, until I went further south down to Sedona (Land of the red rocks) and as I left the interstate at Flagstaff to head south I headed through the mountains at Oak Creek and was totally bowled over at the beauty!
What made the whole road trip though was driving back a couple of days later. As we ascended through the mountains again, the cloud came in and I drove through snow for the next 3 hours before having a rest stop on Route 66!
I would suggest you check the link on the post above also. Quick version though.....if the desire is on Froyo, try unrevoked.com to s-off (and optionally install CWM recovery) and alphrev.nl to adjust the hboot if required depending upon the partition layout of your desired custom rom.
If your desire is already on Gingerbread (i.e. 2nd hand and some clever so and so already flashed the gingerbread update RUU) you may need to s-off and root etc by using revolutionary.io although be warned this is still in beta.