I love this software - it's made windows mobile useable - the best interface i've tried on my Kaiser! It's fast, nice looking and uncluttered. The new version 1.51a seems to be the best so far (Installed it today).
It's a lot quicker to get to the programs you use frequently than with the HTC home screen (Which is limited to just a few programs), plus accessing the comms manager, config stuff, text messages is possible without changing home tabs. HTC Home is ok, but PointUI Home is far better.
Down sides are that there are a few bugs (With my Kaiser sometimes the touch screen does not work in favourites, so need to use D pad or arrows to select, plus sometimes it's hung and I've had to go back to HTC home to sort it).
I'm sure bug's will be ironed out, and new features added to keep this great program moving forward.